Testing new treatments to protect the brain after a stroke
Testing Cerebroprotective Interventions with Rodent Ischemic Stroke Models
This study is looking at new ways to protect the brain during a stroke using animal models, which could help develop better treatments for people who have had a stroke.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11057715 on NIH RePORTER |
What this research studies
This research investigates potential cerebroprotective interventions using advanced animal models of ischemic stroke. By employing techniques such as the intraluminal middle cerebral artery occlusion (MCAO) and blood clot embolic models, the study aims to evaluate how these interventions can mitigate brain injury. The research team, with extensive experience in animal surgeries and stroke models, utilizes state-of-the-art facilities and equipment to monitor blood flow and assess brain function during and after the interventions. The findings could lead to improved strategies for protecting the brain in stroke patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced an ischemic stroke and are seeking innovative treatment options.
Not a fit: Patients who have not experienced a stroke or have other unrelated neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly reduce brain damage and improve recovery outcomes for stroke patients.
How similar studies have performed: Previous research has shown promise in using similar cerebroprotective strategies in animal models, indicating potential for success in human applications.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Hu, Bingren — University of California, San Diego
- Study coordinator: Hu, Bingren
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.