Testing new treatments to protect the brain after a stroke

Y-SPAN: Yale Translational Cerebroprotection Program in SPAN

NIH-funded research Yale University · NIH-11001537

This study is looking at new ways to help protect the brain during and after a stroke, using tests on rodents to find the best treatments that could eventually help people who have had a stroke.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-11001537 on NIH RePORTER

What this research studies

This research focuses on developing and testing new therapies aimed at protecting the brain during and after a stroke. A team of experts at Yale will conduct experiments using rodent models to evaluate the effectiveness of various candidate treatments. The goal is to identify the most promising therapies that can be advanced to clinical trials for stroke patients. The research will also explore innovative methods to improve the testing protocols, ensuring that the selected treatments are likely to be effective in humans.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced a stroke or are at high risk for stroke due to factors like age or comorbidities.

Not a fit: Patients who have not experienced a stroke or do not have risk factors for stroke may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapies that significantly improve recovery and outcomes for stroke patients.

How similar studies have performed: Other research has shown promise in developing cerebroprotective treatments, but this specific approach is part of a novel initiative within the SPAN program.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.