Testing new treatments to protect the brain after a stroke
Official title: Y-SPAN: Yale Translational Cerebroprotection Program in SPAN
Funded at Yale University · NIH-11001537 · Data updated 2026-11-12
This study is looking at new ways to help protect the brain during and after a stroke, using tests on rodents to find the best treatments that could eventually help people who have had a stroke.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | January 1, 2023 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $602,529 |
| NIH project number | 5U01NS130585-03 |
| Project ID | NIH-11001537 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced a stroke or are at high risk for stroke due to factors like age or comorbidities.
✕Less likely to help
Patients who have not experienced a stroke or do not have risk factors for stroke may not benefit from this research.
What this research studies
This research focuses on developing and testing new therapies aimed at protecting the brain during and after a stroke. A team of experts at Yale will conduct experiments using rodent models to evaluate the effectiveness of various candidate treatments. The goal is to identify the most promising therapies that can be advanced to clinical trials for stroke patients. The research will also explore innovative methods to improve the testing protocols, ensuring that the selected treatments are likely to be effective in humans.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve recovery and outcomes for stroke patients.
How similar studies have gone: Other research has shown promise in developing cerebroprotective treatments, but this specific approach is part of a novel initiative within the SPAN program.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Sansing, Lauren H — Yale University
- Study coordinator: Sansing, Lauren H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.