Testing new treatments for Treponema pallidum infection in rabbits.
Official title: Task A95: Minimal Inhibitory Concentration (MIC) Testing and Efficacy Studies in a Rabbit Model of Treponema Pallidum Infection
Funded at Tufts University Boston · NIH-11197722 · Data updated 2026-11-12
This study is looking at how to better treat syphilis by testing new treatments on rabbits, which could help improve options for people dealing with this infection.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tufts University Boston NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 11, 2024 |
| Project end | July 10, 2025 |
| Funding year | 2024 |
| Award (this year) | $106,869 |
| NIH project number | 272201700032I-0-759302400001-1 |
| Project ID | NIH-11197722 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals affected by Treponema pallidum infections or those at risk of contracting syphilis.
✕Less likely to help
Patients with other types of infections or those not affected by Treponema pallidum will not benefit from this research.
What this research studies
This research focuses on developing and refining models to study Treponema pallidum infections, which cause syphilis. By using rabbits as a model organism, the research aims to evaluate the effectiveness of potential therapeutic agents against this infection. Patients may benefit from the insights gained through this research, as it could lead to improved treatment options for syphilis and related conditions. The methodology involves minimal inhibitory concentration (MIC) testing to determine the effectiveness of various treatments.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for syphilis and improve patient outcomes.
How similar studies have gone: Similar research has shown promise in using animal models to evaluate treatments for infectious diseases, indicating a potential for success in this approach.
Where this research is happening
-
Tufts University Boston
Boston, United States Active
Researchers
- Principal investigator: Tzipori, Saul — Tufts University Boston
- Study coordinator: Tzipori, Saul
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.