Testing new treatments for Progressive Supranuclear Palsy.
The Progressive Supranuclear Palsy Clinical Trial Platform (PTP)
This study is creating a new way to test different treatments for Progressive Supranuclear Palsy (PSP) to see how safe and effective they are, and it’s for people living with PSP who want to help find better therapies.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10784249 on NIH RePORTER |
What this research studies
This research aims to develop a clinical trial platform specifically for Progressive Supranuclear Palsy (PSP), a severe neurodegenerative disease. The study will evaluate the safety and effectiveness of multiple therapies simultaneously, including those being tested for Alzheimer's and amyotrophic lateral sclerosis. Patients will be monitored using a specialized rating scale to assess their condition over a 12-month period. The goal is to streamline the process of testing new treatments and to identify effective therapies more quickly.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals diagnosed with mild to moderate Progressive Supranuclear Palsy.
Not a fit: Patients with advanced stages of Progressive Supranuclear Palsy or those with other unrelated neurodegenerative diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options for patients suffering from Progressive Supranuclear Palsy.
How similar studies have performed: Previous research has shown promise in using platform trials for other neurodegenerative diseases, indicating potential success for this approach in PSP.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Boxer, Adam L. — University of California, San Francisco
- Study coordinator: Boxer, Adam L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.