Testing new cancer treatments for children with solid tumors
Official title: Pediatric Preclinical In Vivo Testing Center for Pediatric Sarcoma and Other Solid Tumors
Funded at Sloan-Kettering Inst Can Research · NIH-10861869 · Data updated 2026-11-12
This study is looking for better cancer treatments for kids with solid tumors, like certain sarcomas and rare cancers, by testing new drugs on models created from real patient samples, so that doctors can find the best options for young patients.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | July 1, 2021 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $730,032 |
| NIH project number | 5U01CA263967-04 |
| Project ID | NIH-10861869 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years diagnosed with solid tumors, including sarcomas and other rare pediatric cancers.
✕Less likely to help
Patients with non-solid tumors or those outside the pediatric age range may not benefit from this research.
What this research studies
This research focuses on developing and testing new cancer treatments specifically for children with solid tumors, including various types of sarcomas and rare pediatric cancers. By utilizing over 300 patient-derived xenograft models, the team aims to identify which molecularly targeted drugs are most effective for pediatric patients. The research involves collaboration with leading pediatric oncology programs to ensure that the findings are relevant and can be translated into clinical applications. Patients may benefit from the prioritization of effective treatments tailored to their specific cancer types.
Why it matters
Potential benefit: If successful, this research could lead to more effective and targeted cancer treatments for children, improving their chances of recovery.
How similar studies have gone: Previous research has shown promise in using patient-derived xenograft models for testing cancer treatments, indicating a potential for success in this approach.
Where this research is happening
-
Sloan-Kettering Inst Can Research
New York, United States Active
Researchers
- Principal investigator: Kung, Andrew L — Sloan-Kettering Inst Can Research
- Study coordinator: Kung, Andrew L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.