Testing for HIV in newborns and starting treatment with Dolutegravir early

Point-of-Care HIV Testing and Early Dolutegravir Use for Infants

NIH-funded research Harvard School of Public Health · NIH-10914860

This study is working to make sure that babies in Botswana get tested for HIV right after birth and start on a new, better medicine called Dolutegravir quickly, to help keep them healthy and reduce the risk of serious illness.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionHarvard School of Public Health NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10914860 on NIH RePORTER

What this research studies

This research focuses on improving the diagnosis and treatment of HIV in infants, particularly in Botswana. It aims to implement point-of-care HIV testing at birth and initiate treatment with Dolutegravir, a newer and more effective medication, as soon as possible. The study addresses the urgent need for timely diagnosis and effective treatment to reduce the high mortality rates associated with HIV in infants. By collaborating with local health authorities, the research seeks to integrate these practices into national health programs.

Who could benefit from this research

Good fit: Ideal candidates for this research are newborns diagnosed with HIV within the first few weeks of life.

Not a fit: Patients who are older than one month or those who do not have HIV will not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce HIV-related deaths in infants by ensuring they receive timely and effective treatment.

How similar studies have performed: Previous research has shown promise in using Dolutegravir for treating HIV in infants, but this specific implementation approach is novel.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.