NIH-funded research U01 cooperative agreement

Testing for antibodies to understand COVID-19 exposure and immunity

Official title: SARS-CoV-2 Serological Antibody Testing for Disease Surveillance and Clinical Use

Funded at Kaiser Foundation Research Institute · NIH-11159160 · Data updated 2026-11-12

This study is looking for people aged 7 and up to help us learn more about how many folks in our community have been exposed to COVID-19 and developed antibodies, even if they didn't show any symptoms, so we can better understand immunity over time.

More SARS-CoV-2 research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionKaiser Foundation Research Institute
NIH-funded
Lab location1 site (Oakland, UNITED STATES)
Project startSeptember 1, 2024
Project endAugust 31, 2025
Funding year2024
Award (this year)$302,796
NIH project number3U01CA260584-02S3
Project IDNIH-11159160 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation include individuals aged 7 years and older who are members of Kaiser Permanente Northern California.

Less likely to help

Patients who have not been exposed to SARS-CoV-2 or those outside the age range of 7 years and older may not benefit from this research.

What this research studies

This research investigates the presence of antibodies against SARS-CoV-2 to better understand COVID-19 exposure and immunity in the community. It aims to establish a large-scale cohort of individuals aged 7 years and older from Kaiser Permanente Northern California to assess the prevalence and incidence of antibodies over time. Participants will undergo serological testing to identify those who have been exposed to the virus, including asymptomatic cases, which are often missed by traditional PCR testing. The study will also analyze demographic, behavioral, and clinical data to provide a comprehensive view of the antibody response in the population.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of COVID-19 immunity and inform public health strategies.

How similar studies have gone: Previous research has shown that serological testing can effectively identify COVID-19 exposure and has been used successfully in similar epidemiological studies.

Where this research is happening

  • Kaiser Foundation Research Institute
    Oakland, United States
    Active

Researchers

  • Principal investigator: Skarbinski, Jacek — Kaiser Foundation Research Institute
  • Study coordinator: Skarbinski, Jacek

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.