Testing blood samples to detect advanced adenomas in the colon
Blood-Based Testing for Advanced Adenoma
This study is looking to make it easier to find advanced adenomas, which can lead to colorectal cancer, by using blood tests, and it's for people who have been diagnosed with these growths as well as healthy individuals to help improve screening methods.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10910058 on NIH RePORTER |
What this research studies
This research aims to improve the detection of advanced adenomas, which are precursors to colorectal cancer, using blood tests. The study will collect blood samples from individuals diagnosed with advanced adenomas before and after their polypectomy, as well as from control subjects. By analyzing these samples with innovative molecular detection techniques and machine learning algorithms, the research seeks to validate the effectiveness of blood-based biomarkers in identifying these lesions. This approach may provide a less invasive method for screening and monitoring colorectal cancer risk.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with advanced adenomas who are scheduled for polypectomy.
Not a fit: Patients who do not have advanced adenomas or those who have already undergone treatment for colorectal cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and less invasive screening methods for colorectal cancer, potentially improving early detection and patient outcomes.
How similar studies have performed: Other research has shown promise in using blood-based tests for cancer detection, but the specific application to advanced adenomas is still being validated.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Schoen, Robert E. — University of Pittsburgh at Pittsburgh
- Study coordinator: Schoen, Robert E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.