Testing bladder cancer treatments using urine samples
High throughput nanoplasmonic exosome testing (NEXT) of immunotherapies in bladder cancer
['FUNDING_R01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10914815
This study is looking at a new way to check how well immunotherapy treatments are working for bladder cancer by analyzing tiny particles in urine, which could help doctors make quicker decisions about your care without needing any invasive tests.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS GENERAL HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10914815 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a new method to test the effectiveness of immunotherapies for bladder cancer by analyzing exosomes found in urine. By using advanced nanotechnology, the researchers aim to create a platform that can quickly and accurately assess tumor responses without the need for invasive procedures. This approach could provide earlier insights into how well a treatment is working, allowing for more timely decisions about patient care. The study leverages the unique properties of bladder cancer and its biomarkers found in urine to enhance treatment monitoring.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with bladder cancer who are undergoing immunotherapy.
Not a fit: Patients with non-bladder cancers or those not receiving immunotherapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment strategies for bladder cancer patients.
How similar studies have performed: Previous research has shown promise in using urine exosomes for monitoring other conditions, indicating potential success for this novel approach in bladder cancer.
Where this research is happening
BOSTON, UNITED STATES
- MASSACHUSETTS GENERAL HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CASTRO, CESAR M — MASSACHUSETTS GENERAL HOSPITAL
- Study coordinator: CASTRO, CESAR M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.