Testing a supplement to help manage bone loss in older adults.
Official title: A randomized, double-blind, placebo-controlled, clinical trial of a probiotic/prebiotic supplement for the dietary management of age-related bone loss.
Funded at Hebrew Rehabilitation Center for Aged · NIH-11089476 · Data updated 2026-11-12
This study is looking at how a special probiotic/prebiotic supplement might help improve bone health in women over 60, and it will compare the results with those who take a placebo to see if it really makes a difference.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Hebrew Rehabilitation Center for Aged NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 1, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $645,197 |
| NIH project number | 5R01AG079952-03 |
| Project ID | NIH-11089476 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women over the age of 60 who are experiencing age-related bone loss.
✕Less likely to help
Patients who are not experiencing bone loss or are under 60 years old may not benefit from this research.
What this research studies
This research investigates the effects of a specific probiotic/prebiotic supplement on bone health in older adults, particularly women over 60. Participants will be randomly assigned to receive either the supplement or a placebo, allowing researchers to compare the outcomes. The study aims to measure changes in bone mineral density and strength, as well as other markers related to bone health and gut microbiome function. By focusing on dietary interventions, the research seeks to provide a safer alternative to traditional medications for managing age-related bone loss.
Why it matters
Potential benefit: If successful, this research could offer a new dietary approach to prevent osteoporosis and reduce fracture risk in older adults.
How similar studies have gone: Previous research has shown promising results with similar dietary interventions for bone health, indicating potential for success in this approach.
Where this research is happening
-
Hebrew Rehabilitation Center for Aged
Boston, United States Active
Researchers
- Principal investigator: Sahni, Shivani — Hebrew Rehabilitation Center for Aged
- Study coordinator: Sahni, Shivani
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.