Testing a supplement to help manage bone loss in older adults.

A randomized, double-blind, placebo-controlled, clinical trial of a probiotic/prebiotic supplement for the dietary management of age-related bone loss.

NIH-funded research Hebrew Rehabilitation Center for Aged · NIH-11089476

This study is looking at how a special probiotic/prebiotic supplement might help improve bone health in women over 60, and it will compare the results with those who take a placebo to see if it really makes a difference.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHebrew Rehabilitation Center for Aged NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11089476 on NIH RePORTER

What this research studies

This research investigates the effects of a specific probiotic/prebiotic supplement on bone health in older adults, particularly women over 60. Participants will be randomly assigned to receive either the supplement or a placebo, allowing researchers to compare the outcomes. The study aims to measure changes in bone mineral density and strength, as well as other markers related to bone health and gut microbiome function. By focusing on dietary interventions, the research seeks to provide a safer alternative to traditional medications for managing age-related bone loss.

Who could benefit from this research

Good fit: Ideal candidates for this research are women over the age of 60 who are experiencing age-related bone loss.

Not a fit: Patients who are not experiencing bone loss or are under 60 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could offer a new dietary approach to prevent osteoporosis and reduce fracture risk in older adults.

How similar studies have performed: Previous research has shown promising results with similar dietary interventions for bone health, indicating potential for success in this approach.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.