Testing a smartphone app to help nondaily smokers quit smoking

Randomized clinical trial to test the efficacy of a smartphone app for smoking cessation for nondaily smokers

['FUNDING_R01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10898828

This study is testing a friendly smartphone app called Smiling Instead of Smoking to see if it can help people who smoke occasionally and want to quit by using positive exercises to keep their spirits up, comparing it to regular support methods.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorMASSACHUSETTS GENERAL HOSPITAL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10898828 on ClinicalTrials.gov

What this research studies

This research investigates the effectiveness of a smartphone app called Smiling Instead of Smoking (SiS) designed specifically for nondaily smokers who wish to quit. The app incorporates positive psychology exercises to help users maintain a positive mindset during their quit attempts. By focusing on enhancing engagement and positive affect, the app aims to provide a supportive tool for individuals who may not have found success with traditional smoking cessation methods. Participants will be randomly assigned to either use the app or receive standard care, allowing researchers to assess its impact on smoking cessation rates.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who smoke nondaily and are motivated to quit.

Not a fit: Patients who smoke daily or are not interested in quitting smoking may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a novel and effective tool for nondaily smokers to achieve smoking cessation and improve their overall health.

How similar studies have performed: While previous trials have focused on pharmacological options for nondaily smoking cessation, this behavioral approach using a smartphone app is novel and has not been extensively tested.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.