Testing a new way to treat PTSD in people with substance use issues

Hybrid Effectiveness-Implementation Trial of Massed PTSD Treatment in a Community Substance Use Program

NIH-funded research Rutgers, the State Univ of N.j. · NIH-10953871

This study is looking at a new way to help people with both PTSD and substance use issues by offering more therapy sessions each week, to see if this helps them feel better and stick with their treatment more than the usual once-a-week sessions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRutgers, the State Univ of N.j. NIH-funded
Lab location1 site (Piscataway, United States)
Project IDNIH-10953871 on NIH RePORTER

What this research studies

This research investigates a treatment approach for individuals suffering from both posttraumatic stress disorder (PTSD) and substance use disorders (SUD). It focuses on a method called massed Prolonged Exposure (M-PE), which involves multiple therapy sessions each week, aiming to improve attendance and treatment outcomes. The study will be conducted in a community substance use program, where patients will receive this intensive therapy to address their PTSD symptoms alongside their substance use challenges. By comparing this approach to traditional weekly sessions, the research seeks to find more effective ways to help patients recover.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with both PTSD and substance use disorders who are seeking treatment.

Not a fit: Patients who do not have PTSD or substance use disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment outcomes for patients dealing with both PTSD and substance use disorders.

How similar studies have performed: Previous studies have shown that massed Prolonged Exposure therapy can be effective for PTSD, suggesting this approach may yield positive results for co-occurring disorders.

Where this research is happening

Piscataway, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.