Testing a new way to treat PTSD in people with substance use issues
Official title: Hybrid Effectiveness-Implementation Trial of Massed PTSD Treatment in a Community Substance Use Program
Funded at Rutgers, the State Univ of N.j. · NIH-10953871 · Data updated 2026-11-12
This study is looking at a new way to help people with both PTSD and substance use issues by offering more therapy sessions each week, to see if this helps them feel better and stick with their treatment more than the usual once-a-week sessions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers, the State Univ of N.j. NIH-funded |
| Lab location | 1 site (Piscataway, United States) |
| Project start | September 3, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $754,267 |
| NIH project number | 1R01MH132720-01A1 |
| Project ID | NIH-10953871 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with both PTSD and substance use disorders who are seeking treatment.
✕Less likely to help
Patients who do not have PTSD or substance use disorders may not benefit from this research.
What this research studies
This research investigates a treatment approach for individuals suffering from both posttraumatic stress disorder (PTSD) and substance use disorders (SUD). It focuses on a method called massed Prolonged Exposure (M-PE), which involves multiple therapy sessions each week, aiming to improve attendance and treatment outcomes. The study will be conducted in a community substance use program, where patients will receive this intensive therapy to address their PTSD symptoms alongside their substance use challenges. By comparing this approach to traditional weekly sessions, the research seeks to find more effective ways to help patients recover.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment outcomes for patients dealing with both PTSD and substance use disorders.
How similar studies have gone: Previous studies have shown that massed Prolonged Exposure therapy can be effective for PTSD, suggesting this approach may yield positive results for co-occurring disorders.
Where this research is happening
-
Rutgers, the State Univ of N.j.
Piscataway, United States Active
Researchers
- Principal investigator: Hien, Denise Aimee — Rutgers, the State Univ of N.j.
- Study coordinator: Hien, Denise Aimee
Related research
Other NIH-funded projects on the same topics.
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Written Exposure Therapy for Veterans with PTSD and Substance Use Disorder (brief trauma treatment)
A brief trauma-focused therapy called Written Exposure Therapy is being studied to help veterans who have both PTSD and substance use disorders.
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Web-based training to treat PTSD and substance use together in Veterans
A web-based training resource helps VA clinicians learn how to provide integrated treatment for Veterans with both PTSD and substance use disorders.
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Genetics of PTSD and Substance Use in Diverse Populations
This grant investigates how genes influence PTSD and substance use disorders in diverse groups to improve prevention and treatment.
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Massed PTSD Treatment in a Community Substance Use Program
A community program will test a faster, intensified PTSD treatment delivered alongside substance use care to help people with both conditions.
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Using Written Exposure Therapy to help Veterans with PTSD and Substance Use Disorders
This study is looking at how helpful Written Exposure Therapy can be for Veterans dealing with both PTSD and substance use issues, especially for those in rural areas who might not have easy access to care, to see if it can make their treatment better and improve their quality of life.
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Online training for clinicians to deliver COPE, a combined PTSD and substance-use therapy
This project offers web training to teach VA clinicians how to deliver COPE, a combined Prolonged Exposure therapy for Veterans with PTSD and substance use problems.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.