Testing a new way to help people quit smoking using varenicline medication.
A Translational Randomized Clinical Trial of Varenicline Sampling to Promote Smoking Cessation and Scalable Treatment Dissemination
This study is looking at how trying out the medication varenicline can help people who smoke to quit by letting them test it out before starting a full treatment, while also giving them the freedom to set their own goals and pace, with support from healthcare providers along the way.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical University of South Carolina NIH-funded |
| Lab location | 1 site (Charleston, United States) |
| Project ID | NIH-10867364 on NIH RePORTER |
What this research studies
This research investigates how sampling the medication varenicline can help smokers quit by allowing them to try the medication before committing to a full treatment plan. The approach focuses on empowering smokers to set their own goals and pace for cessation, which may lead to increased motivation and successful quit attempts. The study builds on previous trials that have shown positive results with nicotine replacement therapy, aiming to determine if varenicline can produce similar or better outcomes. Participants will receive support and guidance from healthcare providers throughout the process.
Who could benefit from this research
Good fit: Ideal candidates for this research are adult smokers who are motivated to quit but may lack resources or support to initiate the process.
Not a fit: Patients who are not currently smoking or those who have contraindications to varenicline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a more effective method for smoking cessation, potentially leading to improved health outcomes for smokers.
How similar studies have performed: Previous studies using nicotine replacement therapy sampling have shown success in promoting smoking cessation, suggesting that this approach may be effective with varenicline as well.
Where this research is happening
Charleston, United States
- Medical University of South Carolina — Charleston, United States (Active)
Researchers
- Principal investigator: Carpenter, Matthew J — Medical University of South Carolina
- Study coordinator: Carpenter, Matthew J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.