Testing a new urine test for detecting diabetes during pregnancy
Urine levels of Glycated CD59 for screening and diagnosis of pregnancy-induced glucose intolerance
This study is testing a new urine test that looks for a marker called glycated CD59 to see if it can help identify gestational diabetes more easily and affordably than the usual glucose tests, aiming to improve health for moms and their babies.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11060961 on NIH RePORTER |
What this research studies
This research aims to validate a new biomarker, glycated CD59 (GCD59), found in urine, as a tool for screening and diagnosing pregnancy-induced glucose intolerance, also known as gestational diabetes. The study will assess the effectiveness of this biomarker in various hyperglycemic conditions, focusing on its potential to provide a simpler and more cost-effective alternative to traditional glucose load tests. By improving the screening process, the research seeks to enhance the health outcomes for both mothers and their newborns by identifying those at risk of complications earlier and more accurately.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant women who are at risk for developing glucose intolerance.
Not a fit: Patients who are not pregnant or those who do not have risk factors for gestational diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a more accessible and efficient method for diagnosing gestational diabetes, ultimately improving maternal and fetal health outcomes.
How similar studies have performed: Previous research has shown promise in using novel biomarkers for diabetes detection, indicating potential success for this approach.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Halperin, Jose a — Brigham and Women's Hospital
- Study coordinator: Halperin, Jose a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.