Testing a new treatment for traumatic brain injury
Official title: AcSDKP as a novel treatment for traumatic brain injury
Funded at Henry Ford Health + Michigan State University Health Sciences · NIH-11081050 · Data updated 2026-11-12
This study is looking at a special treatment called AcSDKP to see if it can help people recover better after a traumatic brain injury by protecting the brain and helping it heal.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Henry Ford Health + Michigan State University Health Sciences NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project start | May 1, 2024 |
| Project end | February 28, 2029 |
| Funding year | 2025 |
| Award (this year) | $388,051 |
| NIH project number | 5R01NS132772-02 |
| Project ID | NIH-11081050 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have experienced a traumatic brain injury and are seeking new treatment options.
✕Less likely to help
Patients with mild concussions or those who have not experienced a significant traumatic brain injury may not benefit from this research.
What this research studies
This research investigates the use of a tetrapeptide called AcSDKP as a potential treatment for traumatic brain injury (TBI). The study aims to understand how AcSDKP can enhance recovery after TBI by promoting neuroprotection and neurovascular remodeling. Researchers will conduct experiments to assess the effectiveness of AcSDKP in improving functional outcomes in animal models of TBI, focusing on its ability to reduce brain damage and support healing processes. The findings could lead to new therapeutic options for individuals suffering from TBI.
Why it matters
Potential benefit: If successful, this research could provide a novel treatment option that significantly improves recovery outcomes for patients with traumatic brain injury.
How similar studies have gone: While this approach is novel in the context of TBI, similar therapeutic strategies have shown promise in other neurological conditions.
Where this research is happening
-
Henry Ford Health + Michigan State University Health Sciences
East Lansing, United States Active
Researchers
- Principal investigator: Xiong, Ye — Henry Ford Health + Michigan State University Health Sciences
- Study coordinator: Xiong, Ye
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.