Testing a new treatment for opiate addiction.

A Project to Test the Efficacy and Safety of An Innovative Treatment for Opiate Use Disorders.

NIH-funded research Mindlight, LLC · NIH-10703447

This study is exploring a new way to help people struggling with opiate addiction by using a special light treatment on the brain for just 4 minutes, and it’s designed for those currently using opioids to see if it can help them reduce their drug use and feel better overall.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionMindlight, LLC NIH-funded
Lab location1 site (Newton, United States)
Project IDNIH-10703447 on NIH RePORTER

What this research studies

This research investigates a novel treatment for opiate addiction that utilizes a 4-minute application of near-infrared light to stimulate specific areas of the brain. Patients currently using opioids will receive either the active treatment or a sham treatment over 25 weeks, with regular follow-ups to assess their opioid use, cravings, and overall mental health. The goal is to determine the safety and effectiveness of this innovative approach in reducing drug use and improving psychological well-being.

Who could benefit from this research

Good fit: Ideal candidates are individuals currently using opioids who are not receiving any other treatment for opioid use disorder.

Not a fit: Patients who are not currently using opioids or those already undergoing treatment for opioid use disorder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for individuals struggling with opiate addiction.

How similar studies have performed: Preliminary data from a completed Phase I study suggests that similar approaches have shown promise, indicating potential for success in this research.

Where this research is happening

Newton, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.