Testing a new treatment for mouth sores caused by radiation therapy
Preclinical assessment of a novel compound for treating radiation-induced oral mucositis
This study is looking at a new treatment to help prevent and ease the painful mouth sores that many cancer patients get from radiation therapy, using a special compound that has shown promise in early tests.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sinopia Biosciences, INC. NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project ID | NIH-10822803 on NIH RePORTER |
What this research studies
This research focuses on developing a novel compound to prevent and treat oral mucositis, a painful inflammation and ulceration of the mouth that often occurs in cancer patients undergoing radiation therapy. The study utilizes a computational platform to identify a small molecule that targets specific biological pathways associated with mucositis. Preclinical tests in animal models have shown promising results, indicating that this compound can significantly reduce the duration of mouth sores and may even prevent them altogether. The goal is to provide a safe and effective treatment option for patients suffering from this debilitating side effect.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients undergoing radiation therapy for head and neck cancers who are at risk of developing oral mucositis.
Not a fit: Patients who are not receiving radiation therapy or those with other types of cancer unrelated to head and neck regions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a new treatment that alleviates the pain and complications associated with oral mucositis in cancer patients.
How similar studies have performed: Previous research has shown success in using similar compounds to treat mucositis, but this specific approach is novel and has not yet been tested in clinical settings.
Where this research is happening
San Diego, United States
- Sinopia Biosciences, INC. — San Diego, United States (Active)
Researchers
- Principal investigator: Lloyd, Colton Joseph — Sinopia Biosciences, INC.
- Study coordinator: Lloyd, Colton Joseph
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.