Testing a new treatment for monkeypox virus disease
: A randomized, placebo-controlled trial of the safety and efficacy of tecovirimat for the treatment of patients with monkeypox virus disease
This study is looking at how well a medication called tecovirimat works for treating monkeypox, and it’s for people who have the virus; some will get the real medicine while others will get a dummy pill to see how effective it is in easing symptoms and preventing problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Leidos Biomedical Research, INC. NIH-funded |
| Lab location | 1 site (Frederick, United States) |
| Project ID | NIH-10506292 on NIH RePORTER |
What this research studies
This research investigates the safety and effectiveness of a medication called tecovirimat for treating monkeypox virus disease. The study involves a randomized, placebo-controlled trial, meaning some participants will receive the actual medication while others will receive a placebo to compare results. The trial aims to gather data on how well this treatment works in reducing symptoms and preventing complications associated with monkeypox. Patients will be monitored closely throughout the trial to ensure their safety and to assess the medication's impact.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals diagnosed with monkeypox virus disease, particularly those experiencing symptoms.
Not a fit: Patients who are not infected with monkeypox virus or those who have already received other treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a new effective treatment for monkeypox virus disease, potentially reducing morbidity and mortality associated with the infection.
How similar studies have performed: Previous research has shown promise in developing antiviral treatments for similar viral infections, indicating potential for success in this area.
Where this research is happening
Frederick, United States
- Leidos Biomedical Research, INC. — Frederick, United States (Active)
Researchers
- Principal investigator: Dodd, Lori — Leidos Biomedical Research, INC.
- Study coordinator: Dodd, Lori
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.