Testing a new treatment for hospitalized COVID-19 patients.
ON BEHALF OF NIAID-DCR, FACILITATE THE CONDUCT OF TWO, RANDOMIZED TRIALS AS DETAILED BELOW IN I AND II:I. A RANDOMIZED BLINDED CONTROLLED TRIAL OF TH
['FUNDING_OTHER'] · LEIDOS BIOMEDICAL RESEARCH, INC. · NIH-11199630
This study is looking at whether a special treatment made from antibodies can help adults in the hospital who are dealing with COVID-19, and it will compare the effects of this treatment to a placebo to see how well it works and how safe it is.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LEIDOS BIOMEDICAL RESEARCH, INC. (nih funded) |
| Locations | 1 site (FREDERICK, UNITED STATES) |
| Trial ID | NIH-11199630 on ClinicalTrials.gov |
What this research studies
This research investigates the use of anti-coronavirus hyperimmune intravenous immunoglobulin as a treatment for adults hospitalized with COVID-19. It involves a randomized, double-blind, placebo-controlled trial, meaning that participants will be randomly assigned to receive either the treatment or a placebo without knowing which one they receive. The goal is to assess the safety, tolerability, and effectiveness of this treatment during the early stages of COVID-19 progression. Patients will be monitored closely to gather data on their health outcomes and response to the treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults who are hospitalized and experiencing the early stages of clinical progression of COVID-19.
Not a fit: Patients who are not hospitalized or are in the later stages of COVID-19 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new therapeutic option for improving outcomes in hospitalized COVID-19 patients.
How similar studies have performed: Other research has shown promise in using immunoglobulin therapies for viral infections, suggesting potential for success in this approach.
Where this research is happening
FREDERICK, UNITED STATES
- LEIDOS BIOMEDICAL RESEARCH, INC. — FREDERICK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BASELER, BETH — LEIDOS BIOMEDICAL RESEARCH, INC.
- Study coordinator: BASELER, BETH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.