Testing a new treatment for dengue virus infection
Evaluation of a Candidate Therapeutic for Dengue Virus
This study is testing a new antiviral treatment for dengue fever, and it's looking for healthy adults who haven't been exposed to similar viruses to see how well the treatment works and how safe it is.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10026361 on NIH RePORTER |
What this research studies
This research evaluates a potential antiviral treatment specifically designed to combat dengue virus infection. Healthy adult volunteers who have never been exposed to flavivirus will participate in a controlled challenge model to assess the effectiveness of the therapeutic candidate. Participants will be monitored for their response to the treatment, providing valuable data on its safety and efficacy. The study aims to improve our understanding of how to effectively treat dengue fever.
Who could benefit from this research
Good fit: Ideal candidates for this research are healthy adults aged 21 and older who have never been exposed to flavivirus.
Not a fit: Patients with a history of flavivirus exposure or those with underlying health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a new antiviral treatment for dengue fever, significantly improving patient outcomes.
How similar studies have performed: Previous research has shown promise in developing antiviral treatments for viral infections, but this specific approach is novel.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Karron, Ruth — Johns Hopkins University
- Study coordinator: Karron, Ruth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.