Testing a new low-cost HPV test for cervical cancer screening
Single Visit Clinical Validation of ScreenFire, a Low-Cost HPV Test: Efficacy and Cost Effectiveness (SCALE)
This study is looking at a new, affordable HPV test called AmpFire® to see how well it works for cervical cancer screening when women collect their own samples, making it easier for more people to get tested and treated, especially in low- and middle-income countries.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-11075769 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of a new low-cost HPV test called AmpFire® for cervical cancer screening, particularly in low- and middle-income countries. The study aims to evaluate how well this test performs when women collect their own samples, compared to traditional methods where samples are collected by healthcare providers. By focusing on self-sampling, the research seeks to make cervical cancer screening more accessible and efficient, potentially leading to immediate treatment for those who test positive. The goal is to contribute to the global effort to eliminate cervical cancer by improving screening methods.
Who could benefit from this research
Good fit: Ideal candidates for this research are women, especially in low- and middle-income countries, who are at risk for cervical cancer and may benefit from improved screening methods.
Not a fit: Patients who are not at risk for cervical cancer or those who have already been effectively screened and treated may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a more accessible and effective screening option for cervical cancer, particularly benefiting women in low-resource settings.
How similar studies have performed: Previous research has shown promise in using self-sampling methods for HPV testing, indicating that this approach could be effective and beneficial.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Cremer, Miriam — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Cremer, Miriam
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.