Testing a new long-acting naltrexone implant for opioid use disorder
Evaluation of safety and pharmacokinetics of naltrexone implant
This study is testing a new long-lasting implant that delivers naltrexone to help people with opioid use disorder, making it easier to stick to treatment without needing frequent shots.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10580003 on NIH RePORTER |
What this research studies
This research focuses on developing a long-acting subcutaneous implant of naltrexone, designed to help individuals struggling with opioid use disorder (OUD). The implant aims to provide consistent medication levels for up to six months, reducing the need for frequent injections and improving treatment adherence. By evaluating the safety and pharmacokinetics of this innovative formulation, the study seeks to enhance the effectiveness of OUD treatment and potentially prevent relapses. Participants will be monitored closely to assess how well the implant works in managing their condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with opioid use disorder who are seeking treatment options.
Not a fit: Patients who are not struggling with opioid use disorder or those who are not suitable for naltrexone treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a more effective and convenient treatment option for individuals with opioid use disorder, potentially reducing relapse rates.
How similar studies have performed: Previous clinical trials of similar long-acting naltrexone formulations have shown promise in other countries, indicating potential for success in this research.
Where this research is happening
New York, United States
- New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC — New York, United States (Active)
Researchers
- Principal investigator: Bisaga, Adam — New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
- Study coordinator: Bisaga, Adam
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.