Testing a new drug to relieve pain from endometriosis
Validating SER-014, a TRPV1 antagonist, to treat endometriosis
This study is testing a new drug called SER-014 to see if it can help relieve pain from endometriosis without the risks of addiction, offering a safer option for women who struggle with this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Serentrix, LLC NIH-funded |
| Lab location | 1 site (Exton, United States) |
| Project ID | NIH-10916997 on NIH RePORTER |
What this research studies
This research focuses on validating SER-014, a drug that blocks the TRPV1 receptor, which is involved in pain and inflammation associated with endometriosis. Endometriosis is a painful condition affecting many women, and current treatments often fall short, leading to reliance on opioids. By targeting the TRPV1 receptor, SER-014 aims to provide a non-addictive alternative for pain relief. The study will involve assessing the drug's effectiveness and safety in patients suffering from this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are women diagnosed with endometriosis who experience chronic pain and have not found relief from existing treatments.
Not a fit: Patients who do not have endometriosis or those whose pain is not related to this condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could offer a new, non-addictive treatment option for women suffering from endometriosis-related pain.
How similar studies have performed: Other research has shown promise in targeting TRPV1 for pain management, suggesting that this approach could be effective.
Where this research is happening
Exton, United States
- Serentrix, LLC — Exton, United States (Active)
Researchers
- Principal investigator: Bhargava, Kumaril — Serentrix, LLC
- Study coordinator: Bhargava, Kumaril
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.