Testing a new bone scaffold to prevent infections in craniofacial surgeries
Official title: Determining the Efficacy of a Novel Apatite-Based Antimicrobial Bone Scaffold for Craniofacial Surgical Applications
Funded at University of Utah · NIH-10573777 · Data updated 2026-11-12
This study is testing a new type of bone scaffold that helps heal big bone injuries while also fighting off infections, making it easier for patients to recover without needing extra surgeries.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $423,500 |
| NIH project number | 1R21DE032503-01 |
| Project ID | NIH-10573777 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced traumatic craniofacial injuries resulting in critical-size bone defects.
✕Less likely to help
Patients with non-traumatic bone conditions or those who do not require surgical intervention for bone defects may not benefit from this research.
What this research studies
This research investigates a novel apatite-based antimicrobial bone scaffold designed to address critical-size bone defects that often occur after traumatic injuries. The approach focuses on creating a bone substitute that not only supports bone regeneration but also possesses antimicrobial properties to prevent infections during the healing process. By using this engineered scaffold, the research aims to reduce the need for multiple surgeries and improve outcomes for patients with severe bone injuries. The methodology includes testing the scaffold's mechanical strength, porosity, and bioactivity to ensure it can effectively replace traditional graft materials.
Why it matters
Potential benefit: If successful, this research could significantly improve healing outcomes and reduce complications for patients undergoing craniofacial surgeries.
How similar studies have gone: Previous research has shown promise in using engineered bone scaffolds for similar applications, indicating potential for success in this novel approach.
Where this research is happening
-
University of Utah
Salt Lake City, United States Active
Researchers
- Principal investigator: Jeyapalina, Sujee — University of Utah
- Study coordinator: Jeyapalina, Sujee
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.