Testing a medication to help adults quit using e-cigarettes
Investigating Efficacious E-Cigarette Interventions and Cessation Effects on Cancer-Related Biomarkers: A Randomized Trial of Varenicline in Adults
['FUNDING_R01'] · YALE UNIVERSITY · NIH-11022368
This study is looking at how well the medication varenicline can help adults who only use e-cigarettes quit, and it involves a friendly group of participants who will either take the medication or a placebo to see what works best.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | YALE UNIVERSITY (nih funded) |
| Locations | 1 site (NEW HAVEN, UNITED STATES) |
| Trial ID | NIH-11022368 on ClinicalTrials.gov |
What this research studies
This research investigates the effectiveness of varenicline, a medication commonly used for smoking cessation, in helping adults who exclusively use e-cigarettes to quit. The study will involve a randomized clinical trial with 326 participants aged 18 and older, some of whom may have a history of cigarette smoking. Participants will receive either varenicline or a placebo, and their progress will be monitored to assess changes in cancer-related biomarkers and cessation rates. The goal is to provide evidence-based methods for e-cigarette cessation, addressing a growing public health concern.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 18 and older who use e-cigarettes daily and are seeking to quit.
Not a fit: Patients who do not use e-cigarettes or are under 18 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a proven method for adults to quit e-cigarettes, potentially reducing cancer risk and improving overall health.
How similar studies have performed: Previous studies have shown promising results for varenicline in smoking cessation, suggesting potential success for its use in e-cigarette cessation as well.
Where this research is happening
NEW HAVEN, UNITED STATES
- YALE UNIVERSITY — NEW HAVEN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FUCITO, LISA M — YALE UNIVERSITY
- Study coordinator: FUCITO, LISA M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.