Temple Emergency Care Network (Temple-SIREN)
Temple Strategies to Innovate EmeRgENcy Care Clinical Trials Network (Temple-SIREN)
This network tests new emergency treatments and ways of caring for people who come to emergency departments with sudden heart, breathing, brain, or trauma problems in the Philadelphia region.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Temple Univ of the Commonwealth NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11299061 on NIH RePORTER |
What this research studies
If you come to a participating emergency department or are cared for by a participating EMS team, you may be at a hospital that is part of this Temple-led network running emergency care studies. The network brings together high-volume emergency and trauma centers across Philadelphia, New Jersey, Delaware, and Maryland and uses a hub-and-spoke model centered at Temple to coordinate work. Teams use a shared informatics system to find eligible patients quickly, provide training and regular oversight to study staff, and follow common procedures to enroll people and collect data. The goal is to speed promising treatments from the lab to the bedside and improve how acute heart, lung, brain, and trauma emergencies are treated.
Who could benefit from this research
Good fit: People who come to participating emergency departments or are treated by participating EMS systems with acute cardiopulmonary problems, neurological emergencies, or traumatic brain injury are the most likely candidates.
Not a fit: People without acute emergency conditions, those treated outside the participating region or hospitals, or those who do not meet specific study eligibility rules may not benefit directly.
Why it matters
Potential benefit: If successful, the network could speed access to better emergency treatments and improve survival and recovery after serious heart, breathing, brain, or trauma emergencies.
How similar studies have performed: Other regional emergency research networks have successfully increased enrollment and led to important treatment advances, though results depend on each specific trial.
Where this research is happening
Philadelphia, United States
- Temple Univ of the Commonwealth — Philadelphia, United States (Active)
Researchers
- Principal investigator: Gentile, Nina T — Temple Univ of the Commonwealth
- Study coordinator: Gentile, Nina T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.