TEDDY follow-up and new case‑control group for young-onset diabetes
Limited Competition: Continued Follow-up of Subjects and Initiation of a Second Case-control Cohort in The Environmental Determinants of Diabetes in The Young Study (TEDDY)
This project continues tracking children in the TEDDY diabetes program and adds a new comparison group to learn why some children develop early autoimmune diabetes while others do not.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of South Florida NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-11388693 on NIH RePORTER |
What this research studies
If your child is part of TEDDY, the project keeps collecting their health information and lab results over time and manages those data centrally. The Data Coordinating Center will receive, secure, clean, and analyze information from TEDDY clinical sites and will monitor data quality and staff adherence to the protocol. The project will start a second nested case‑control group that compares children who develop diabetes-related autoantibodies or type 1 diabetes with similar children who do not. Study teams will protect confidentiality, support communications and study materials, and share findings with investigators and participants through the TEDDY network and website.
Who could benefit from this research
Good fit: Ideal candidates are children already enrolled in TEDDY (or their families) who are being followed for development of diabetes-related autoantibodies or early type 1 diabetes.
Not a fit: Adults with long-standing or brittle diabetes and people not enrolled in TEDDY are not eligible and would not directly benefit from participating in this follow-up effort.
Why it matters
Potential benefit: If successful, this work could improve understanding of environmental triggers and early markers of type 1 diabetes in children, helping with earlier detection and prevention efforts.
How similar studies have performed: The ongoing TEDDY project has already produced important findings about early autoantibodies and environmental links, and this continuation builds on that prior success.
Where this research is happening
Tampa, United States
- University of South Florida — Tampa, United States (Active)
Researchers
- Principal investigator: Krischer, Jeffrey P — University of South Florida
- Study coordinator: Krischer, Jeffrey P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.