TEDDY: continued follow-up and a new case-control group for young-onset diabetes
Limited Competition: Continued Follow-up of Subjects and Initiation of a Second Case-control Cohort in The Environmental Determinants of Diabetes in The Young Study (TEDDY)
This project continues long-term tracking of children at risk for early-onset (type 1) diabetes and adds a new matched group to learn what environmental differences exist between those who develop diabetes and those who do not.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of South Florida NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-11388703 on NIH RePORTER |
What this research studies
If you or your child are in TEDDY, the team will keep collecting health information, blood samples, and tests for diabetes-related autoantibodies over time. The Data Coordinating Center at the University of South Florida will manage and protect your data, monitor data quality across sites, and provide statistical support. A second nested case-control cohort will match children who develop diabetes with similar children who do not to look for environmental and other differences. Researchers will share findings, study materials, and communications with participants and may use results to guide earlier detection or prevention strategies.
Who could benefit from this research
Good fit: Ideal candidates are children already enrolled in TEDDY or those at genetic risk for early-onset type 1 diabetes who can continue regular follow-up and provide periodic samples.
Not a fit: Adults without childhood-onset type 1 diabetes, people not enrolled at a TEDDY clinical center, and those needing immediate treatment rather than long-term follow-up are unlikely to benefit directly.
Why it matters
Potential benefit: Could help identify environmental or early biological markers of type 1 diabetes that lead to better prevention or earlier diagnosis for children.
How similar studies have performed: Previous long-term cohort work, including earlier TEDDY results, has identified autoantibodies and possible environmental links, and this project builds on that track record by adding a focused case-control comparison.
Where this research is happening
Tampa, United States
- University of South Florida — Tampa, United States (Active)
Researchers
- Principal investigator: Krischer, Jeffrey P — University of South Florida
- Study coordinator: Krischer, Jeffrey P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.