Team managing development of an antibody-based vaginal contraceptive
Core A: Administration
['FUNDING_OTHER'] · BOSTON UNIVERSITY MEDICAL CAMPUS · NIH-11168790
This project helps create a vaginal film that delivers a human antibody to clump and immobilize sperm for people seeking a non-hormonal contraceptive.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON UNIVERSITY MEDICAL CAMPUS (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11168790 on ClinicalTrials.gov |
What this research studies
This administrative core organizes and supports projects developing ZB-06, a thin vaginal film that releases the Human Contraception Antibody (HCA) to rapidly agglutinate and immobilize sperm. The team coordinates clinical and laboratory work, maintains the clinical database, and provides biostatistical support so studies run smoothly. They convene an executive committee and an external scientific advisory panel to track milestones and guide experimental changes. Their role is to ensure data and materials are shared across projects and that the development and testing proceed in an integrated, timely way.
Who could benefit from this research
Good fit: Ideal candidates would be sexually active people with a vagina who want a non-hormonal, on-demand contraceptive and can attend clinic visits in the Boston area.
Not a fit: People trying to become pregnant, those seeking protection against sexually transmitted infections, or those allergic to product components are unlikely to benefit from this contraceptive approach.
Why it matters
Potential benefit: If successful, this could offer a fast-acting, on-demand, non-hormonal contraceptive option for people who want local protection without systemic hormones.
How similar studies have performed: Antibody-based contraceptives are a relatively new approach with promising laboratory and early-stage preclinical results but limited prior success in large human trials.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON UNIVERSITY MEDICAL CAMPUS — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ANDERSON, DEBORAH J — BOSTON UNIVERSITY MEDICAL CAMPUS
- Study coordinator: ANDERSON, DEBORAH J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.