Targeting viruses in the human microbiome to understand immune responses
Official title: Antibody targeting of the virome
Funded at University of Utah · NIH-10987732 · Data updated 2026-11-12
This study is looking at how certain viruses, called bacteriophages, in our bodies can affect the way our immune system grows and works, especially in kids under 11, to help us understand how they might play a role in keeping us healthy.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | September 15, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $1,046,329 |
| NIH project number | 1U01AT012990-01 |
| Project ID | NIH-10987732 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who are healthy and have not been diagnosed with any immune-related conditions.
✕Less likely to help
Patients with pre-existing immune disorders or those outside the age range of 0-11 years may not benefit from this research.
What this research studies
This research investigates the role of viruses, specifically bacteriophages, in the human microbiome and their impact on immune system development. By analyzing the virome, which includes the vast array of viruses present in healthy individuals, the study aims to uncover how these viruses influence immune responses and contribute to health. The research employs advanced sequencing techniques to characterize these viral populations and their interactions with the immune system, particularly in children under 11 years old.
Why it matters
Potential benefit: If successful, this research could lead to new insights into how viruses affect immune health, potentially informing treatments for various diseases.
How similar studies have gone: While the study of bacteriophages is emerging, previous research has shown promising results in understanding their role in health and disease, indicating potential for success in this novel approach.
Where this research is happening
-
University of Utah
Salt Lake City, United States Active
Researchers
- Principal investigator: Round, June Louise — University of Utah
- Study coordinator: Round, June Louise
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.