Targeting viruses in the human microbiome to understand immune responses
Antibody targeting of the virome
['FUNDING_U01'] · UNIVERSITY OF UTAH · NIH-10987732
This study is looking at how certain viruses, called bacteriophages, in our bodies can affect the way our immune system grows and works, especially in kids under 11, to help us understand how they might play a role in keeping us healthy.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF UTAH (nih funded) |
| Locations | 1 site (SALT LAKE CITY, UNITED STATES) |
| Trial ID | NIH-10987732 on ClinicalTrials.gov |
What this research studies
This research investigates the role of viruses, specifically bacteriophages, in the human microbiome and their impact on immune system development. By analyzing the virome, which includes the vast array of viruses present in healthy individuals, the study aims to uncover how these viruses influence immune responses and contribute to health. The research employs advanced sequencing techniques to characterize these viral populations and their interactions with the immune system, particularly in children under 11 years old.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who are healthy and have not been diagnosed with any immune-related conditions.
Not a fit: Patients with pre-existing immune disorders or those outside the age range of 0-11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into how viruses affect immune health, potentially informing treatments for various diseases.
How similar studies have performed: While the study of bacteriophages is emerging, previous research has shown promising results in understanding their role in health and disease, indicating potential for success in this novel approach.
Where this research is happening
SALT LAKE CITY, UNITED STATES
- UNIVERSITY OF UTAH — SALT LAKE CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ROUND, JUNE LOUISE — UNIVERSITY OF UTAH
- Study coordinator: ROUND, JUNE LOUISE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.