Targeting the immune system to treat Alzheimer's disease
A Systems Approach to Targeting Innate Immunity in AD
['FUNDING_U01'] · MAYO CLINIC JACKSONVILLE · NIH-10475289
This study is looking at how the immune system changes in people with Alzheimer's disease to find new ways to treat or prevent the condition, and it's for anyone interested in understanding more about Alzheimer's and potential new therapies.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MAYO CLINIC JACKSONVILLE (nih funded) |
| Locations | 1 site (JACKSONVILLE, UNITED STATES) |
| Trial ID | NIH-10475289 on ClinicalTrials.gov |
What this research studies
This research focuses on identifying and validating therapeutic targets within the innate immune system that may play a role in Alzheimer's disease (AD). By leveraging existing data and generating new insights, the team aims to understand how immune responses are altered in AD and whether these changes contribute to the disease process. The project involves analyzing various patient data to differentiate between normal aging and pathological changes associated with AD. Ultimately, the goal is to find new ways to treat or prevent Alzheimer's by targeting these immune pathways.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults diagnosed with Alzheimer's disease or those showing early signs of cognitive decline.
Not a fit: Patients with other forms of dementia unrelated to Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve outcomes for patients with Alzheimer's disease.
How similar studies have performed: Previous research has shown promise in targeting immune pathways for neurodegenerative diseases, suggesting potential for success in this approach.
Where this research is happening
JACKSONVILLE, UNITED STATES
- MAYO CLINIC JACKSONVILLE — JACKSONVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ERTEKIN-TANER, NILUFER — MAYO CLINIC JACKSONVILLE
- Study coordinator: ERTEKIN-TANER, NILUFER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer's Disease, Alzheimer disease