Targeting the different states of glioblastoma tissue
MOSAIC: Targeting the Tissue State
['FUNDING_OTHER'] · MAYO CLINIC ARIZONA · NIH-11186082
This study is looking at how different cells in glioblastoma, a tough type of brain cancer, work together and affect treatment, with the goal of finding better ways to help patients like you.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MAYO CLINIC ARIZONA (nih funded) |
| Locations | 1 site (SCOTTSDALE, UNITED STATES) |
| Trial ID | NIH-11186082 on ClinicalTrials.gov |
What this research studies
This research investigates glioblastoma (GBM), a type of brain cancer characterized by its diverse cellular makeup, which complicates treatment. The project aims to understand how various tumor and non-tumor cells interact within the tumor microenvironment, influencing tumor growth and response to therapies. By analyzing the cellular composition and the signals exchanged between these cells, researchers hope to identify new therapeutic strategies. The study utilizes advanced techniques like single nucleus RNA sequencing to explore changes in tissue states before and after treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with glioblastoma who are undergoing treatment.
Not a fit: Patients with other types of brain tumors or those who are not currently receiving treatment for glioblastoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for glioblastoma by targeting its unique cellular environments.
How similar studies have performed: Previous research has shown promise in understanding tumor microenvironments, suggesting that this approach could lead to significant advancements in glioblastoma treatment.
Where this research is happening
SCOTTSDALE, UNITED STATES
- MAYO CLINIC ARIZONA — SCOTTSDALE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TRAN, NHAN L — MAYO CLINIC ARIZONA
- Study coordinator: TRAN, NHAN L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.