Targeting specific kinases to treat breast cancer in Hispanic and Latina women.
Official title: Targeting centrosome‐mitotic kinases as a novel therapeutic approach against breast cancers in Hispanic/Latinas.
Funded at Ponce School of Medicine · NIH-10918342 · Data updated 2026-11-12
This study is looking at how specific proteins related to cell structures might affect breast cancer, especially in Hispanic and Latina women who are more likely to develop aggressive types of the disease, with the goal of finding new ways to improve treatment for them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ponce School of Medicine NIH-funded |
| Lab location | 1 site (Ponce, United States) |
| Project start | September 15, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $486,917 |
| NIH project number | 5R01CA266046-03 |
| Project ID | NIH-10918342 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Hispanic and Latina women, particularly those diagnosed with aggressive forms of breast cancer.
✕Less likely to help
Patients who do not identify as Hispanic or Latina or those with non-aggressive breast cancer may not benefit from this research.
What this research studies
This research focuses on understanding how certain kinases related to centrosomes contribute to breast cancer, particularly in Hispanic and Latina women who are at higher risk. The study investigates the role of these kinases in tumor development and progression, especially in aggressive forms of breast cancer like triple-negative breast cancer. By analyzing tumor samples from diverse populations, the researchers aim to identify potential therapeutic targets that could improve treatment outcomes for these patients.
Why it matters
Potential benefit: If successful, this research could lead to new targeted therapies that significantly improve survival rates for Hispanic and Latina women with breast cancer.
How similar studies have gone: Previous research has shown promising results in targeting similar kinases in other populations, suggesting potential for success in this novel approach.
Where this research is happening
-
Ponce School of Medicine
Ponce, United States Active
Researchers
- Principal investigator: Saavedra, Harold I — Ponce School of Medicine
- Study coordinator: Saavedra, Harold I
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.