Targeting social avoidance behavior in patients with depression and anxiety

Personalized Neuromodulation Targeting Dysregulated Motivational Responses Underlying Social Avoidance Behavior

NIH-funded research Auburn University at Auburn · NIH-10784274

This study is looking at how avoiding social situations affects people with depression and social anxiety, and it will use a special treatment to help improve their motivation and social interactions, making it easier for them to connect with others and feel better overall.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionAuburn University at Auburn NIH-funded
Lab location1 site (Auburn, UNITED STATES)
Project IDNIH-10784274 on NIH RePORTER

What this research studies

This research investigates how social avoidance behavior (SAB) affects individuals with Major Depressive Disorder (MDD) and Social Anxiety Disorder (SAD). It aims to use transcranial magnetic stimulation (TMS) to modify specific brain circuits involved in motivation and social interactions. By focusing on the connectivity between key brain regions, the study seeks to develop personalized interventions that can effectively reduce SAB, which is often resistant to current treatments. Patients will participate in targeted interventions designed to improve their social engagement and overall mental health.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Major Depressive Disorder or Social Anxiety Disorder who experience significant social avoidance behavior.

Not a fit: Patients who do not have internalizing disorders or those without social avoidance behavior may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that significantly improve social functioning and reduce symptoms in patients with depression and anxiety.

How similar studies have performed: Previous research has shown promise in using neuromodulation techniques like TMS to address similar behavioral issues, suggesting potential for success in this novel approach.

Where this research is happening

Auburn, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.