Targeting receptors to treat gigantism in children
Official title: Improved Targeting of Somatostatin Receptors for Pediatric Conditions
Funded at Baylor College of Medicine · NIH-11075916 · Data updated 2026-11-12
This study is looking at ways to help kids with gigantism by exploring how certain receptors in the body can better control growth hormone levels, especially for those who can’t have surgery, so we can create safer and more effective treatments for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | May 1, 2024 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $162,051 |
| NIH project number | 5R00HD107581-04 |
| Project ID | NIH-11075916 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years diagnosed with gigantism due to pituitary adenomas.
✕Less likely to help
Patients who do not have gigantism or related conditions may not benefit from this research.
What this research studies
This research focuses on improving treatments for gigantism, a condition in children caused by excessive growth hormone levels. The approach involves studying somatostatin receptors, which are crucial for regulating growth hormone, particularly in cases where surgery is not an option. By investigating the structure and function of these receptors, the research aims to develop better therapeutic options that minimize side effects and enhance treatment efficacy for affected children.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer treatments for children suffering from gigantism.
How similar studies have gone: Previous research has shown promise in targeting somatostatin receptors for similar conditions, indicating potential for success in this approach.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Robertson, Michael — Baylor College of Medicine
- Study coordinator: Robertson, Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.