Targeting receptors to treat gigantism in children
Improved Targeting of Somatostatin Receptors for Pediatric Conditions
This study is looking at ways to help kids with gigantism by exploring how certain receptors in the body can better control growth hormone levels, especially for those who can’t have surgery, so we can create safer and more effective treatments for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11075916 on NIH RePORTER |
What this research studies
This research focuses on improving treatments for gigantism, a condition in children caused by excessive growth hormone levels. The approach involves studying somatostatin receptors, which are crucial for regulating growth hormone, particularly in cases where surgery is not an option. By investigating the structure and function of these receptors, the research aims to develop better therapeutic options that minimize side effects and enhance treatment efficacy for affected children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years diagnosed with gigantism due to pituitary adenomas.
Not a fit: Patients who do not have gigantism or related conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer treatments for children suffering from gigantism.
How similar studies have performed: Previous research has shown promise in targeting somatostatin receptors for similar conditions, indicating potential for success in this approach.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Robertson, Michael — Baylor College of Medicine
- Study coordinator: Robertson, Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.