Targeting lymph nodes with a new treatment for follicular lymphoma
Lymph node-targeted multistage chemoimmunotherapy for lymphoma
This study is testing a new way to treat follicular lymphoma by sending special cancer-fighting drugs right to the lymph nodes where the cancer is, and combining them with radiation to make the treatment work better and have fewer side effects.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia Institute of Technology NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10814934 on NIH RePORTER |
What this research studies
This research focuses on developing a novel approach to treat follicular lymphoma, a type of cancer that affects B lymphocytes. The team aims to deliver immunotherapy drugs directly to the lymph nodes where the cancer resides, using a two-stage drug delivery system. By combining these drugs with radiation therapy, they hope to enhance the treatment's effectiveness while minimizing side effects. The research will be conducted using a preclinical model that closely mimics human disease, allowing for a thorough evaluation of the new therapy's potential.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with follicular lymphoma who have not responded well to existing treatments.
Not a fit: Patients with other types of lymphoma or those who are not eligible for immunotherapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and less toxic treatments for patients with follicular lymphoma.
How similar studies have performed: Previous research has shown promise in using targeted therapies and immunotherapy for lymphoma, suggesting that this approach could be effective.
Where this research is happening
Atlanta, United States
- Georgia Institute of Technology — Atlanta, United States (Active)
Researchers
- Principal investigator: Thomas, Susan Napier — Georgia Institute of Technology
- Study coordinator: Thomas, Susan Napier
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.