Targeting lung tumor environments to inhibit cancer growth
Toward Clinical Trial: AXL-STAT3 Targeting of Lung Tumor Microenvironments
This study is looking at how certain signals in lung tumors help them grow and spread, and it hopes to find new ways to block those signals, which could lead to better treatments for lung cancer patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-11101315 on NIH RePORTER |
What this research studies
This research investigates how specific signaling pathways, AXL and STAT3, contribute to the growth and spread of lung tumors. By examining the interactions between different cell types within the tumor microenvironment, the study aims to disrupt the communication that supports cancer progression. Patients may benefit from new therapeutic strategies that target these pathways, potentially leading to improved outcomes in lung cancer treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with lung cancer who may benefit from novel therapeutic approaches targeting tumor microenvironments.
Not a fit: Patients with non-cancerous conditions or those not diagnosed with lung cancer may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for lung cancer by disrupting the tumor-supporting environment.
How similar studies have performed: Other research has shown promising results in targeting similar signaling pathways in cancer treatment, indicating potential for success in this approach.
Where this research is happening
San Antonio, United States
- University of Texas Hlth Science Center — San Antonio, United States (Active)
Researchers
- Principal investigator: Taverna, Josephine a — University of Texas Hlth Science Center
- Study coordinator: Taverna, Josephine a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.