Targeting lipid metabolism to control enterovirus infections
Infection-specific lipid metabolism as a target to control enterovirus infections
['FUNDING_R01'] · UNIV OF MARYLAND, COLLEGE PARK · NIH-11044053
This study looks at how enteroviruses change the way our cells handle fats to help them multiply, and by figuring this out, researchers hope to find new ways to treat infections that could help patients feel better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF MARYLAND, COLLEGE PARK (nih funded) |
| Locations | 1 site (COLLEGE PARK, UNITED STATES) |
| Trial ID | NIH-11044053 on ClinicalTrials.gov |
What this research studies
This research investigates how enteroviruses manipulate lipid metabolism in human cells to facilitate their replication. By understanding the specific lipid and protein compositions of the viral replication organelles, researchers aim to identify potential therapeutic targets. The study focuses on the role of lipid droplets and the enzymes involved in lipid metabolism during enterovirus infections. Patients may benefit from new antiviral strategies that disrupt these processes.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with enterovirus infections or those at high risk for such infections.
Not a fit: Patients with infections caused by viruses other than enteroviruses may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of novel antiviral therapies for enterovirus infections.
How similar studies have performed: Other research has shown promise in targeting viral replication mechanisms, suggesting that this approach could be effective.
Where this research is happening
COLLEGE PARK, UNITED STATES
- UNIV OF MARYLAND, COLLEGE PARK — COLLEGE PARK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BELOV, GEORGE A. — UNIV OF MARYLAND, COLLEGE PARK
- Study coordinator: BELOV, GEORGE A.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.