Targeting interactions between HIV and host proteins to stop HIV replication.
RNA-mimicry to guide the intra-cellular targeting of host virus protein and viral RNA-protein interactions to inhibit HIV replication.
This study is looking at how HIV works with our body's proteins to find new ways to stop the virus from making copies of itself, which could lead to better treatments for people living with HIV.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project ID | NIH-11070307 on NIH RePORTER |
What this research studies
This research aims to explore how HIV interacts with host cell proteins and to develop new treatments that can disrupt these interactions. By focusing on specific proteins involved in HIV replication, the researchers hope to create inhibitors that can effectively prevent the virus from replicating within the body. The approach involves studying the molecular mechanisms of these interactions and testing potential drugs that can interfere with them, which could lead to more effective therapies for HIV patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are seeking new treatment options.
Not a fit: Patients who are not infected with HIV or those who have already achieved viral suppression with existing therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new antiviral therapies that significantly reduce HIV replication and improve health outcomes for patients living with HIV.
How similar studies have performed: Previous research has shown promise in targeting host-virus interactions as a viable strategy to inhibit HIV replication, indicating that this approach has potential for success.
Where this research is happening
Bronx, United States
- Albert Einstein College of Medicine — Bronx, United States (Active)
Researchers
- Principal investigator: Kalpana, Ganjam V — Albert Einstein College of Medicine
- Study coordinator: Kalpana, Ganjam V
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.