Targeting inflammation in cancer using nanoparticles
Official title: Reveal myeloid cell-mediated targeting through nano-bio interface
Funded at University of Florida · NIH-10939693 · Data updated 2026-11-12
This study is looking at tiny particles that can be directed to areas in the body where there’s inflammation, like in cancer or other inflammatory conditions, to help deliver treatments more effectively.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | September 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $373,375 |
| NIH project number | 1R35GM155275-01 |
| Project ID | NIH-10939693 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with cancer or inflammatory disorders who may benefit from targeted nanomedicine therapies.
✕Less likely to help
Patients without cancer or inflammatory conditions are unlikely to benefit from this research.
What this research studies
This research investigates how ultra-small nanoparticles can be effectively targeted to inflamed tissues in cancer and inflammatory disorders. By studying the interactions between myeloid cells, such as inflammatory monocytes, and these nanoparticles, the research aims to improve the delivery of treatments directly to areas of inflammation. The approach involves understanding how proteins in the blood interact with nanoparticles, which can influence their behavior and effectiveness. The ultimate goal is to develop better nanotherapeutics that can specifically target inflammation.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for cancer and inflammatory disorders by improving how therapies are delivered to affected tissues.
How similar studies have gone: Previous research has shown promise in using nanoparticles for targeted therapy, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Zhang, Fan — University of Florida
- Study coordinator: Zhang, Fan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.