Targeting drugs more effectively in the body using non-covalent methods
Non-Covalent Molecular Recognition for Drug Targeting in the Body
This study is looking at a new way to deliver medications directly to the parts of the body that need them most, while causing less harm to healthy tissues, so patients can get better treatments with fewer side effects.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Notre Dame NIH-funded |
| Lab location | 1 site (Notre Dame, United States) |
| Project ID | NIH-10873968 on NIH RePORTER |
What this research studies
This research focuses on improving how drugs are delivered to specific sites in the body while minimizing harm to healthy tissues. It explores a novel approach using non-covalent molecular recognition, which allows for better distribution and faster clearance of therapeutic agents. By modifying drugs with affinity motifs, the research aims to enhance the targeting of these drugs to desired tissues, potentially allowing for repeated dosing and reduced toxicity. Patients may benefit from more effective treatments with fewer side effects.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals requiring targeted drug therapies for various diseases where current delivery methods are inadequate.
Not a fit: Patients who do not require targeted drug delivery or those with conditions that do not respond to drug therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective drug delivery systems that improve treatment outcomes and reduce side effects for patients.
How similar studies have performed: Other research has shown promise in using non-covalent methods for drug targeting, indicating that this approach could be a significant advancement in the field.
Where this research is happening
Notre Dame, United States
- University of Notre Dame — Notre Dame, United States (Active)
Researchers
- Principal investigator: Webber, Matthew — University of Notre Dame
- Study coordinator: Webber, Matthew
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.