NIH-funded research R01 grant

Targeting different types of small cell lung cancer with new treatments

Official title: Combining CDK7 and MUC1-C inhibition to target different subtypes of small cell lung cancer

Funded at New York University School of Medicine · NIH-11043435 · Data updated 2026-11-12

This study is looking at new ways to treat small cell lung cancer by testing combinations of treatments that target specific proteins, and it’s for patients who want to explore innovative options to improve their chances of recovery.

More Lung Cancer research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York University School of Medicine
NIH-funded
Lab location1 site (New York, United States)
Project startMarch 1, 2024
Project endFebruary 28, 2029
Funding year2025
Award (this year)$673,898
NIH project number5R01CA282437-02
Project IDNIH-11043435 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults diagnosed with small cell lung cancer, particularly those whose disease has not responded well to standard treatments.

Less likely to help

Patients with non-small cell lung cancer or those who have already exhausted all treatment options may not benefit from this research.

What this research studies

This research focuses on small cell lung cancer (SCLC), a highly aggressive form of lung cancer that often recurs after initial treatment. The study aims to explore new treatment strategies by combining inhibitors that target specific proteins involved in the cancer's growth and survival. By understanding the different subtypes of SCLC and their unique characteristics, the research seeks to develop more effective therapies that could improve patient outcomes. Patients may have the opportunity to participate in trials that test these innovative treatment approaches.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for small cell lung cancer, potentially improving survival rates and quality of life for patients.

How similar studies have gone: Other research has shown promise in targeting specific pathways in small cell lung cancer, suggesting that this approach could lead to significant advancements in treatment.

Where this research is happening

  • New York University School of Medicine
    New York, United States
    Active

Researchers

  • Principal investigator: Wong, Kwok Kin — New York University School of Medicine
  • Study coordinator: Wong, Kwok Kin

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.