Targeting cancer stem cells in glioblastoma
Targeting Glioblastoma Stem Cells
['FUNDING_OTHER'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10982682
This study is looking at how glioblastoma, a tough type of brain cancer, grows and resists treatment, especially as people age, to find better ways to fight it by understanding the special cells that help the tumor survive.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-10982682 on ClinicalTrials.gov |
What this research studies
This research investigates the complex nature of glioblastoma, a highly aggressive brain cancer, by focusing on the role of cancer stem cells and how aging affects tumor development and treatment resistance. The study aims to understand the cellular and molecular mechanisms that allow these tumors to thrive despite treatment efforts. By exploring the unique environment of neural stem cells and their interactions within glioblastoma, the research seeks to develop more effective therapeutic strategies that can overcome the challenges posed by these resilient cancer cells.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients diagnosed with glioblastoma, particularly those who are older and may have a more complex tumor biology.
Not a fit: Patients with other types of brain tumors or those who are not diagnosed with glioblastoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for glioblastoma, improving survival rates and quality of life for patients.
How similar studies have performed: Previous research has shown promise in targeting cancer stem cells in other types of cancers, suggesting that this approach may also be effective for glioblastoma.
Where this research is happening
PITTSBURGH, UNITED STATES
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RICH, JEREMY N — UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- Study coordinator: RICH, JEREMY N
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Treatment, Cancers