Targeting brain cell growth in mice affected by prenatal alcohol exposure

Therapeutic Targeting of Adult Hippocampal Neurogenesis in a Mouse Model of FASD

['FUNDING_FELLOWSHIP'] · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · NIH-10998022

This study is looking at how certain treatments, like medications or changes in the environment, can help mice that were affected by alcohol before birth grow new brain cells, with the hope that it could lead to better brain function for people with fetal alcohol spectrum disorder (FASD).

Quick facts

Phase['FUNDING_FELLOWSHIP']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF NEW MEXICO HEALTH SCIS CTR (nih funded)
Locations1 site (ALBUQUERQUE, UNITED STATES)
Trial IDNIH-10998022 on ClinicalTrials.gov

What this research studies

This research investigates how different interventions, such as medications or environmental changes, can help restore the growth of new brain cells in mice that were exposed to alcohol before birth. The study focuses on understanding how prenatal alcohol exposure affects the brain's ability to generate new neurons, particularly in the hippocampus, which is crucial for learning and memory. By using a mouse model, the researchers aim to identify effective treatments that could potentially improve brain function in individuals with fetal alcohol spectrum disorder (FASD).

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with fetal alcohol spectrum disorder or those who have experienced prenatal alcohol exposure.

Not a fit: Patients who do not have a history of prenatal alcohol exposure or related neurodevelopmental disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapeutic strategies for improving brain health in individuals affected by fetal alcohol spectrum disorder.

How similar studies have performed: Previous research has shown promise in using pharmacological interventions to enhance neurogenesis in various models, suggesting potential for success in this approach.

Where this research is happening

ALBUQUERQUE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.