Targeting and manipulating specific brain cells using RNA technology
RNA-programmable cell type targeting and manipulation across vertebrate nervous systems
['FUNDING_OTHER'] · DUKE UNIVERSITY · NIH-10350096
This study is testing a new tool called CellREADR that helps scientists better target and study different types of brain cells, which could improve our understanding of how the brain works and how to treat brain disorders.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DUKE UNIVERSITY (nih funded) |
| Locations | 1 site (DURHAM, UNITED STATES) |
| Trial ID | NIH-10350096 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a new technology called CellREADR, which allows for precise targeting and manipulation of various neuronal cell types in the brain. By utilizing RNA engineering, this method overcomes limitations of traditional DNA-based approaches, making it easier and more efficient to access and study different brain cells. The technology is designed to be scalable and applicable across various animal species, potentially enhancing our understanding of brain function and disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with neurological disorders or conditions that affect specific neuronal cell types.
Not a fit: Patients with conditions unrelated to neuronal cell type dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating neurological conditions by enabling targeted therapies that address specific brain cell types.
How similar studies have performed: Other research has shown promise in RNA-based targeting methods, but this approach represents a novel advancement in the field.
Where this research is happening
DURHAM, UNITED STATES
- DUKE UNIVERSITY — DURHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HUANG, Z JOSH — DUKE UNIVERSITY
- Study coordinator: HUANG, Z JOSH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.