Targeting advanced prostate cancer by inhibiting lipid signaling pathways
Targeting Castration Resistant Prostate Cancer via Potent Inhibition of Signaling Lipids
This study is looking at how advanced prostate cancer, especially in African American patients, uses fats to grow and survive when standard treatments stop working, and it hopes to find new ways to block this process to improve treatment options.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10911825 on NIH RePORTER |
What this research studies
This research focuses on advanced prostate cancer that has become resistant to standard treatments. It investigates how cancer cells use lipids for growth and survival, particularly in African American patients who are disproportionately affected by this disease. The study aims to inhibit specific signaling pathways that promote lipid metabolism in these cancer cells, potentially leading to new treatment options. By understanding the role of certain transcription factors in this process, the research seeks to develop targeted therapies that could improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are men diagnosed with metastatic castration-resistant prostate cancer, especially those of African American descent.
Not a fit: Patients with early-stage prostate cancer or those who do not have castration-resistant disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients with castration-resistant prostate cancer, particularly among African American men who face higher risks.
How similar studies have performed: Other research has shown promising results in targeting lipid metabolism in cancer, indicating that this approach may be effective.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Kaochar, Salma — Baylor College of Medicine
- Study coordinator: Kaochar, Salma
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.