Targeting a specific protein to treat lung cancer
Targeting lysine acetyltransferase MOF/KAT8 in lung cancer
['FUNDING_R01'] · GEORGE WASHINGTON UNIVERSITY · NIH-10999406
This study is looking at a protein called MOF/KAT8 to see how it affects lung cancer and how it might help us find new ways to treat the disease.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | GEORGE WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (WASHINGTON, UNITED STATES) |
| Trial ID | NIH-10999406 on ClinicalTrials.gov |
What this research studies
This research investigates the role of the MOF/KAT8 protein in lung cancer, focusing on how it regulates gene expression and cellular processes related to tumor development. By manipulating the acetylation of proteins, the study aims to develop new therapeutic strategies for lung cancer treatment. The research involves both laboratory experiments and mouse models to understand the mechanisms by which MOF influences cancer progression and to explore its potential as a treatment target.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with lung cancer, particularly those with adenocarcinoma.
Not a fit: Patients with non-cancerous conditions or those with lung cancer types not related to the mechanisms being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new and more effective treatments for lung cancer.
How similar studies have performed: Other research has shown promising results in targeting similar proteins for cancer treatment, indicating potential for success in this approach.
Where this research is happening
WASHINGTON, UNITED STATES
- GEORGE WASHINGTON UNIVERSITY — WASHINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SETO, EDWARD — GEORGE WASHINGTON UNIVERSITY
- Study coordinator: SETO, EDWARD
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: anti-cancer therapy, Cancer Cause, cancer diagnosis, Cancer Etiology, Cancer Prognosis