Targeting a specific protein to fight pancreatic cancer
Targeting cadherin-11 in pancreatic cancer
This study is looking at how a protein called cadherin-11, which is found in high amounts in pancreatic cancer, can be targeted to help improve treatments and make them more effective for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Diviner Therapeutics, LLC NIH-funded |
| Lab location | 1 site (Fairfax, United States) |
| Project ID | NIH-10546886 on NIH RePORTER |
What this research studies
This research focuses on pancreatic cancer, which is a leading cause of cancer-related deaths. It aims to understand how a protein called cadherin-11, which is found in high levels in pancreatic tumors, can be targeted to improve treatment outcomes. The approach involves studying the interactions between cancer cells, immune cells, and supportive cells in the tumor environment, rather than just removing supportive cells. By modulating these interactions, the research seeks to limit tumor growth and improve patient survival.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with pancreatic cancer, particularly those who have limited treatment options.
Not a fit: Patients with early-stage pancreatic cancer or those who do not have cadherin-11 expression in their tumors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for pancreatic cancer, potentially improving survival rates and quality of life for patients.
How similar studies have performed: While targeting cadherin-11 is a novel approach, similar strategies in other cancers have shown promise, indicating potential for success in this area.
Where this research is happening
Fairfax, United States
- Diviner Therapeutics, LLC — Fairfax, United States (Active)
Researchers
- Principal investigator: Dakshanamurthy, Sivanesan — Diviner Therapeutics, LLC
- Study coordinator: Dakshanamurthy, Sivanesan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.