Targeting a protein to improve treatment for colon cancer
Colon cancer nanotherapy targeting STRAP
['FUNDING_OTHER'] · BIRMINGHAM VA MEDICAL CENTER · NIH-10768573
This study is looking at a protein called STRAP to see how it affects colon cancer and why some treatments don’t work as well; by learning more about STRAP, the researchers hope to create better therapies that could help patients respond better to their current treatments.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BIRMINGHAM VA MEDICAL CENTER (nih funded) |
| Locations | 1 site (BIRMINGHAM, UNITED STATES) |
| Trial ID | NIH-10768573 on ClinicalTrials.gov |
What this research studies
This research investigates the role of a protein called STRAP in colon cancer progression and treatment resistance. By understanding how STRAP influences cancer cell growth and survival, the researchers aim to develop targeted therapies that can enhance the effectiveness of existing treatments. The study involves both laboratory experiments and animal models to explore how reducing STRAP levels can make cancer cells more susceptible to chemotherapy. Patients may benefit from new treatment strategies that specifically address STRAP's role in their cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with colon cancer, especially those exhibiting high levels of STRAP expression.
Not a fit: Patients with non-cancerous conditions or those with colon cancer that does not involve STRAP may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for colon cancer, particularly for patients who currently struggle with drug resistance.
How similar studies have performed: Other research has shown promising results in targeting similar pathways in cancer treatment, suggesting potential for success in this approach.
Where this research is happening
BIRMINGHAM, UNITED STATES
- BIRMINGHAM VA MEDICAL CENTER — BIRMINGHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DATTA, PRAN K — BIRMINGHAM VA MEDICAL CENTER
- Study coordinator: DATTA, PRAN K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, neoplasm/cancer, in situ cancer, Rectal Cancer