Talking about buprenorphine and methadone to start opioid treatment

Conversations can save lives: TALKing About Buprenorphine & methadone for Opioid Use Treatment Initiation (TALK ABOUT)

NIH-funded research Baystate Medical Center, INC. · NIH-11161482

This project helps people with opioid use disorder in the emergency department start lifesaving medications like buprenorphine or methadone by improving conversations about treatment options.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBaystate Medical Center, INC. NIH-funded
Lab location1 site (Springfield, United States)
Project IDNIH-11161482 on NIH RePORTER

What this research studies

You would be offered a clearer, shared conversation with emergency department clinicians about buprenorphine and methadone as options for opioid treatment. Researchers will develop and pilot communication tools and decision-making guides to help clinicians invite patients into choosing the treatment that fits them. The work will take place in the emergency department and track whether more people leave with a plan for medication and whether they are still in treatment after 30 days. Feedback from patients and clinicians will be used to refine the tools so they can be used more widely if effective.

Who could benefit from this research

Good fit: Ideal candidates are adults with opioid use disorder who present to the emergency department and are open to discussing medication options such as buprenorphine or methadone.

Not a fit: People without opioid use disorder, those not seen in participating emergency departments, or those already stably engaged in medication treatment may not benefit from this project.

Why it matters

Potential benefit: If successful, more people with opioid use disorder may start and stay on medications that reduce overdose risk and improve survival.

How similar studies have performed: Previous programs that start buprenorphine in the ED have increased 30-day treatment retention and shared decision-making has improved patient engagement in other areas, so this approach builds on promising prior work.

Where this research is happening

Springfield, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.